Disulfide- and terminal alkyne-functionalized magnetic silica particles for enrichment of azido glycopeptides.
نویسندگان
چکیده
Disulfide- and terminal alkyne-modified magnetic silica particles (DA-MSPs) were synthesized and used to covalently capture and reductively release azido glycopeptides via click chemistry and dithiothreitol treatment. Using DA-MSPs, an efficient and specific enrichment method for separating azido glycopeptides has been developed.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 47 شماره
صفحات -
تاریخ انتشار 2012